A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed …

M Peters, R Breinbauer

Index: Peters, Martin; Breinbauer, Rolf Tetrahedron Letters, 2010 , vol. 51, # 50 p. 6622 - 6625

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Citation Number: 7

Abstract

The selective alkylation of functionalized 2-(1H-imidazol-1-yl) pyridines 1 furnishes 3-methyl- 1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron- donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C–H activated borylation of arenes with its current scope and limitations are reported.