Bioorganic & medicinal chemistry

Synthesis and antimicrobial profile of N-substituted imidazolium oximes and their monoquaternary salts against multidrug resistant bacteria

R Odžak, M Skočibušić, A Maravić

Index: Odzak, Renata; Skocibusic, Mirjana; Maravic, Ana Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 23 p. 7499 - 7506

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Citation Number: 10

Abstract

Abstract Two different series of N-substituted imidazolium oximes and their monoquaternary salts were synthesized and biologically tested with respect to their ability to inhibit growth a diverse panel of antibiotic susceptible Gram-positive and antibiotic resistant Gram-negative bacteria as well fungal strains. The newly synthesized compounds were analyzed by spectral studies to confirm their structure. The preliminary results showed that all ...

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