Tetrahedron letters

6, 7, 14, 15-Tetrahydro-15aH-azocino [1, 2-a: 6, 5-b′] diindole. Synthesis of a novel pentacyclic ring system

K Sripha, DP Zlotos, S Buller, K Mohr

Index: Sripha, Kittisak; Zlotos, Darius P.; Buller, Stefan; Mohr, Klaus Tetrahedron Letters, 2003 , vol. 44, # 38 p. 7183 - 7186

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Citation Number: 9

Abstract

In search of new lead structures for potent allosteric enhancers of antagonist binding to muscarinic M2 receptors, a novel heterocyclic ring system, 6, 7, 14, 15-tetrahydro-15aH- azocino [1, 2-a: 6, 5-b′] diindole, has been synthesized. The new ring skeleton was obtained from indol-2-yl-acetic acid in three steps.

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