Expeditious preparation of isoxazoles from Δ 2-isoxazolines as advanced intermediates for functional materials

…, RR da Rosa, PH Schneider, IH Bechtold, J Eccher…

Index: Vilela, Guilherme D.; Da Rosa, Rafaela R.; Schneider, Paulo H.; Bechtold, Ivan H.; Eccher, Juliana; Merlo, Aloir A. Tetrahedron Letters, 2011 , vol. 52, # 49 p. 6569 - 6572

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Citation Number: 29

Abstract

A collection of isoxazoles derivatives has been efficiently synthesized in three steps. The oximation reaction of aldehydes followed by nitrile oxide [3+ 2] 1, 3-dipolar cycloaddition and MnO2-oxidation reaction furnished the title compounds which were purified by simple filtration on celite®.

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