ARKIVOC

Directed lithiation of simple aromatics and heterocycles for synthesis of substituted derivatives

GA El-Hiti, MB Alshammari, AM Masmali

Index: Smith, Keith; El-Hiti, Gamal A.; Abdel-Megeed, Mohamed F.; Abdo, Mohamed A. Journal of Organic Chemistry, 1996 , vol. 61, # 2 p. 656 - 661

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Abstract

Abstract Directed lithiation of substituted aromatics and heterocycles containing a directing metalating group with alkyllithium in anhydrous tetrahydrofuran or diethyl ether at low temperature provides the corresponding lithium intermediates. Reaction of the lithium