Synthetic communications

Preparation of ethyl 5-iodo-1 H-indole-2-carboxylate

DC Beshore, CJ Dinsmore

Index: Beshore, Douglas C.; Dinsmore, Christopher J. Synthetic Communications, 2003 , vol. 33, # 14 p. 2423 - 2427

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Citation Number: 7

Abstract

Abstract A facile, two step procedure for the preparation of ethyl 5-iodo-1 H-indole-2- carboxylate (1) from commercially available ethyl 1 H-indole-2-carboxylate is described herein, employing a regioselective C 3, C 5-bisiodination followed by zinc-mediated C 3- dehalogenation.

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