Steric and electronic limitations of the SRN1 reaction between p-nitrobenzylic substrates and tertiary carbanions

BD Jacobs, SJ Kwon, LD Field, RK Norris, D Randles…

Index: Jacobs, Bruce D.; Kwon, Soon-Jae; Field, Leslie D.; Norris, Robert K.; Randles, David; et al. Tetrahedron Letters, 1985 , vol. 26, # 29 p. 3495 - 3498

Full Text: HTML

Citation Number: 9

Abstract

Abstract The S RN 1 reaction between sterically hindered p-nitrobenzylic substrates and tertiary carbanions gives C-alkylated products whose yields depend on the steric bulk of both the benzylic substrate and the carbanion, and on the nature of the groups in the carbanion.