Synthesis and study of antiaggregative and hypotensive activity of condensed isoquinoline derivatives

AG Mikhailovskii, BY Syropyatov, VS Shklyaev…

Index: Mikhailovskii; Syropyatov; Shklyaev; Timofeeva; Dolzhenko Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 8 p. 419 - 421

Full Text: HTML

Citation Number: 1

Abstract

Previously we have studied the antiaggregative properties of some aromatic phenanthridine derivatives [I]. The other condensed compounds of the isoquinoline series, such as benzo[f]isoquinolines and hydrogenated phenanthridines, are less studied in this respect [2 -4]. As is known, the presence of isoquinoline fragment in a molecule favors manifestations of the hypotensive activity [5, 6]. The purpose of this work was to study the antiaggregative and hypoteusive properties of ...