Journal of organometallic chemistry

Palladium-catalysed coupling of terminal alkynes with aryl halides aided by catalytic zinc

GT Crisp, PD Turner, KA Stephens

Index: Crisp, Geoffrey T.; Turner, Peter D.; Stephens, Kim A. Journal of Organometallic Chemistry, 1998 , vol. 570, # 2 p. 219 - 224

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Citation Number: 72

Abstract

The ability of terminal alkynes to couple with aryl halides using the traditional methodology of a palladium catalyst (either palladium(0) or (II)), a base (frequently a secondary or tertiary amine) and copper iodide (for the generation of the copper acetylide intermediate), has been known for many years [1]. Several recent alternatives have been reported to this general theme and all proceed well in the absence of a copper co-catalyst but with modified reaction ...