Organic letters

Reductive cleavage of NO bonds using Samarium (II) iodide in a traceless release strategy for solid-phase synthesis

RM Myers, SP Langston, SP Conway, C Abell

Index: Myers, Rebecca M.; Langston, Steven P.; Conway, Simon P.; Abell, Chris Organic Letters, 2000 , vol. 2, # 10 p. 1349 - 1352

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Citation Number: 34

Abstract

The objective of the research described herein was to develop a simple traceless linker that could be used for bidirectional elaboration from a central nitrogen atom. To this end we have extended the usefulness of polymer-supported hydroxylamine. This linker has previously been described by others and has been used in the synthesis of tripeptide and sulfonamido hydroxamic acid derivatives, 3 and in the synthesis of a range of carbonyl-containing compounds. 4 An N- ...

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