Selective monobenzoylation of 1, 2-and 1, 3-diols catalyzed by Me2SnCl2 in water (organic solvent free) under mild conditions

W Muramatsu, JM William…

Index: Muramatsu, Wataru; William, Julius M.; Onomura, Osamu Journal of Organic Chemistry, 2012 ,  vol. 77,  # 1  p. 754 - 759

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Citation Number: 14

Abstract

We have developed an efficient method for selective monobenzoylation of 1, 2-and 1, 3- diols in water catalyzed by Me2SnCl2. Treatment of 1, 2-and 1, 3-diols with benzoyl chlorides, DMT-MM, and potassium carbonate in the presence of a catalytic amount of Me2SnCl2 and DMAP in water at room temperature gave monobenzoates in up to 97% yield.