Organic letters

Asymmetric transfer hydrogenation of ketimines using well-defined iron (II)-based precatalysts containing a PNNP ligand

AA Mikhailine, MI Maishan, RH Morris

Index: Mikhailine, Alexandre A.; Maishan, Mazharul I.; Morris, Robert H. Organic Letters, 2012 ,  vol. 14,  # 17  p. 4638 - 4641

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Citation Number: 58

Abstract

Well-defined iron (II)-based complexes containing PNNP ligands catalyze a highly enantioselective reduction of N-(diphenylphosphinoyl)-and N-(p-tolylsulphonyl)-ketimines. Under mild conditions and low catalyst loading, the ketimines are successfully reduced to the corresponding amines in enantiomeric excess ranging from 94 to 99%.