Tetrahedron letters

β-Cyclodextrin promoted aza-Michael addition of amines to conjugated alkenes in water

K Surendra, NS Krishnaveni, R Sridhar, KR Rao

Index: Surendra; Krishnaveni, N. Srilakshmi; Sridhar; Rao, K. Rama Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2125 - 2127

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Citation Number: 122

Abstract

Highly efficient and environmentally benign aza-Michael additions of amines to α, β- unsaturated compounds catalyzed by β-cyclodextrin in water to produce the corresponding β-amino compounds in excellent yields under mild conditions are described. β-Cyclodextrin can be recovered and reused in subsequent reactions without loss of activity.