Synthetic Communications

Diethyl 3-Bromopropene Phosphonate an Alkylative 8-Keto Phosphonate Equivalent

AJ Poss, MS Smyth

Index: Poss, A. J.; Smyth, M. S. Synthetic Communications, 1987 , vol. 17, # 14 p. 1735 - 1740

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Citation Number: 9

Abstract

ABSTRACT: A description of the preparation of diethyl 3-bromopropene phosphonate, 1 , is reported. The use of this reagent as an acetone equivalent for the annulation of five-membered rings is described. ... One of the simplest strategies for annulation of a cyclopentenone ring to a carbon skeleton involves alkylation of a ketone with an acetonyl equivalent, unmasking the new appendage into a carbonyl species and ... Diethyl 3-bromopropene phosphonate, 1, ...

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