Two Anhydrous and a Trihydrate Form of Tilorone Dihydrochloride: Hydrogen-Bonding Patterns and Reversible Hydration/Dehydration Solid-State Transformation

…, IS Lonin, KA Paseshnichenko, AV Mironov…

Index: Chernyshev, Vladimir V.; Yatsenko, Alexandr V.; Pirogov, Sergey V.; Nikulenkova, Tamara F.; Tumanova, Ekaterina V.; Lonin, Ivan S.; Paseshnichenko, Ksenia A.; Mironov, Andrei V.; Velikodny, Yurii A. Crystal Growth and Design, 2012 , vol. 12, # 12 p. 6118 - 6125

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Citation Number: 4

Abstract

Two anhydrous and a trihydrate form of tilorone dihydrochloride were obtained, and their crystal structures were established from X-ray powder diffraction. Different crystal packing and hydrogen-bonding patterns of two anhydrates elucidate the observed difference in their stability to hydration at ambient conditions.