Synthesis of a 3-ether analogue of lipid A

M Shiozaki, Y Kobayashi, M Arai, N Ishida…

Index: Shiozaki, Masao; Kobayashi, Yoshiyuki; Arai, Masami; Ishida, Noboru; Hiraoka, Tetsuo; et al. Carbohydrate Research, 1991 , vol. 222, p. 69 - 82

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Citation Number: 5

Abstract

Abstract Lipid A 3-ether analogues were synthesized from allyl 2-deoxy-4, 6-O- isopropylidene-2-trifluoroacetamido-α-d-glucopyranoside and 3, 4, 6-tri-O-acetyl-2- trifluoroacetamido-α-d-glucopyranosyl bromide. The compound lost completely the endotoxic activity.

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