Synthesis and anti-angiogenetic activity evaluation of N-(3-aryl acryloyl) aminosaccharide derivatives

K Liu, S Yao, Y Lou, Y Xu

Index: Liu, Kun; Yao, Shuowei; Lou, Yinghan; Xu, Yungen Carbohydrate Research, 2013 , vol. 381, p. 83 - 92

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Citation Number: 4

Abstract

Abstract In order to find novel potent inhibitors for signal pathways of FGF/FGFR, nineteen N- (3-aryl acryloyl) aminosaccharide derivatives were designed and synthesized based on the binding sites of FGF and oligosaccharides of heparin. Their structures were confirmed by IR,