A short synthesis of the antimitotic allylic diepoxide functional array of spatol

KK Murthi, RG Salomon

Index: Murthi, Krishna K.; Salomon, Robert G. Tetrahedron Letters, 1994 , vol. 35, # 4 p. 517 - 520

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Citation Number: 11

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An α-lithio epoxide intermediate provides a highly stereocontrolled synthesis of the spatol allylic diepoxide, a functional array that is uniquely effective at inhibiting mitosis. ... An α-lithio epoxide 10p is a novel and effective reagent for conversion of 2-substituted acroleins into ...