Synthesis and tubulin binding of 4'-(1-azi-2, 2, 2-trifluoroethyl) oncodazole, a photolabile analog of oncodazole

DL Ladd, PB Harrsch, LI Kruse

Index: Journal of Organic Chemistry, , vol. 53, # 2 p. 417 - 420

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Citation Number: 12

Abstract

... [3H]Oncodazole was prepared by the Department of Synthetic Chemistry, Smith Kline & French Laboratories. ... The organic layer was washed with H,O, dried over MgS04, and concentrated to yield 13.10 g (89%) of ketal-protected product as an amber oil. ... Page 4. 420 J. Org. ...