A reliable multigram synthesis of (±) doxazosin

G Kumaraswamy, AK Das, N Jena

Index: Kumaraswamy; Das; Jena, Nivedita Organic Preparations and Procedures International, 2003 , vol. 35, # 6 p. 603 - 608

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Citation Number: 5

Abstract

(*) Doxazosin mesylate (6* mesylate), an important drug of the quinazoline family in current use€ or the treatment of hypertension has also been proven effective for the treatment of benign prostatic hyperplasia (BPH). Doxazosin mesylate displays high binding affinity for a,- adrenoceptor, with no significant activity at q-sites. This mode of action provides appropriate therapy which is being increasingly employed in order to ameliorate hemodynamic ...