Convenient syntheses of 3, 6??dialkyl??1, 4??dihydroxy??2, 5??dioxopiperazines
A Ohta, F Yamamoto, Y Arimura…
Index: Ohta, Akihiro; Yamamoto, Fusako; Arimura, Yasuhiko; Watanabe, Tokuhiro Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 781 - 784
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Citation Number: 6
Abstract
Abstract Some 3, 6-dialkyl-1, 4-dihydroxy-2, 5-dioxopiperazines were conveniently prepared from the corresponding 3, 6-dialkyl-2, 5-dichloropyrazines via their 1, 4-dioxides and 3, 6- dialkyl-2, 5-dihydroxypyrazine 1, 4-dioxides. On the basis of the examination of pmr, tlc, and glc of the 2, 5-dioxopiperazines derived from the products, it was clarified that all the products were cis-diastereomers.