Transition??Metal??Catalyzed Cyclopropanation of Nonactivated Alkenes in Dibromomethane with Triisobutylaluminum

G Brunner, S Elmer, F Schröder

Index: Brunner, Gerhard; Elmer, Susanne; Schroeder, Fridtjof European Journal of Organic Chemistry, 2011 , # 24 p. 4623 - 4633

Full Text: HTML

Citation Number: 3

Abstract

Abstract The cyclopropanation of nonactivated alkenes with inexpensive triisobutylaluminum (TIBA), in dibromomethane as solvent and reagent, is efficiently catalyzed by FeCl 3 at ambient temperature. Catalytic amounts of Cu I salts, CpTiCl 3, and [CpFe (CO) 2] 2 are similarly effective. 2-Methylpropane, generated after quench of excess TIBA can be trapped, and excess dibromomethane can be recycled, which makes the method industrially ...