Use of bridge annelation to retain the syn-stereochemistry of [mn] metacyclophane derivatives: a route to an elusive syn-[2.2] metacyclophanediene

YH Lai, SM Lee

Index: Lai, Yee-Hing; Lee, Siok-Mun Journal of Organic Chemistry, 1988 , vol. 53, # 19 p. 4472 - 4476

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Citation Number: 12

Abstract

The parent [2.2] metacyclophane was first reported as early as in 1899 by Pellegrin.'It has subsequently been shown to exist in the anti-stepped conformation la in both solution (lH NMR analysis) 2 and the solid state (X-ray crystallographic~ tudies).~ The synthesis4 of the