Synthesis of a series of carbon??14 labeled tetrahydropyrido [4, 3??d] pyrimidin??4 (3H)??ones

…, N Saemian, RP McGeary, G Shirvani

Index: Arjomandi, Omid Khalili; Saemian, Nader; McGeary, Ross P.; Shirvani, Gholamhossein Journal of Labelled Compounds and Radiopharmaceuticals, 2013 , vol. 56, # 14 p. 722 - 725

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Abstract

The fused skeleton piperidine-pyrimidones have been a rich source of biologically active molecular entities and are related to a wide family of compounds with well-known pharmacological properties. 1-5 Among the different substitution patterns that are known, tetrahydropyrido [4, 3-d] pyrimidines are important because of their potential biological and pharmaceutical activities. The tetrahydropyridopyrimidine core is a key pharmacophore in ...