Tetrahedron

A concise, regio and stereoselective route to fluorinated protoberberines via tandem addition-cyclisation reactions of phthalide anions with 3, 4-dihydroisoquinolines

RN Warrener, L Liu, RA Russell

Index: Warrener, Ronald N.; Liu, Ligong; Russell, Richard A. Tetrahedron, 1998 , vol. 54, # 26 p. 7485 - 7496

Full Text: HTML

Citation Number: 18

Abstract

A series of fluorinated protoberberines have been prepared by condensing fluorinated phthalide anions with 6, 7-dimethyoxydihydroisoquinoline. The spectroscopy and stereochemistry of the products are discussed and the stereochemical outcome of the reactions rationalised.

Related Articles:

Regioselectivity of metal hydride reductions of unsymmetrically substituted cyclic anhydrides. systems where" steric hindrance along the preferred reaction path" …

[Kayser, Margaret M.; Morand, Peter Canadian Journal of Chemistry, 1980 , vol. 58, p. 2484 - 2490]

Regioselectivity of metal hydride reductions of unsymmetrically substituted cyclic anhydrides. systems where" steric hindrance along the preferred reaction path" …

[Canadian Journal of Chemistry, , vol. 58, p. 2484 - 2490]

Synthesis of 8-Fluoro-10-methyl-1, 2-benzanthracene1

[Journal of Organic Chemistry, , vol. 26, p. 3208 - 3211]

More Articles...