Structure-activity relationship among purpurinimides and bacteriopurpurinimides: Trifluoromethyl substituent enhanced the photosensitizing efficacy

A Gryshuk, Y Chen, LN Goswami…

Index: Journal of Medicinal Chemistry, , vol. 50, # 8 p. 1754 - 1767

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Citation Number: 44

Abstract

... Journal of Medicinal Chemistry. ... The Schlosser group at the Swiss Federal Institute of Technology, Lausanne, have screened a series of organofluorine compounds for medical applications, and in certain structures, it was observed that introducing fluorine into the lead ...

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