Fluorophore-linked zinc (II) dipicolylamine coordination complexes as sensors for phosphatidylserine-containing membranes
C Lakshmi, RG Hanshaw, BD Smith
Index: Lakshmi; Hanshaw, Roger G.; Smith, Bradley D. Tetrahedron, 2004 , vol. 60, # 49 p. 11307 - 11315
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Citation Number: 68
Abstract
A series of Zn2+–2, 2′-dipicolylamine (Zn2+–DPA) coordination complexes with an attached NBD fluorophore are synthesized and evaluated as fluorescent sensors. The sensors do not respond to vesicles composed of zwitterionic phosphatidylcholine, but the NBD fluorescence emission is enhanced in the presence of anionic vesicles. A sensor with two Zn2+–DPA units and a hydrophilic tris (ethyleneoxy) linker produced a larger ...
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