Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones

A Avino, I Navarro, J Farrera-Sinfreu, M Royo…

Index: Avino, Anna; Navarro, Isabel; Farrera-Sinfreu, Josep; Royo, Miriam; Aymami, Juan; Delgado, Antonio; Llebaria, Amadeu; Albericio, Fernando; Eritja, Ramon Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 7 p. 2306 - 2310

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Citation Number: 13

Abstract

A method for the preparation of oligomers by linking chromophore units is described. Specifically, the synthesis of chromophore units having a protected-hydroxyl group and a phosphoramidite function is described, along with a method to link several units using solid- phase phosphite-triester protocols.

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