Convenient synthesis of 4-methylhistamine and racemic. alpha., 4-dimethylhistamine and. alpha., 4-dimethylhistidine

DD Davey, WC Lumma Jr

Index: Journal of Organic Chemistry, , vol. 54, # 13 p. 3211 - 3213

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Citation Number: 11

Abstract

... The organic layer was further extracted with cold HzO and dried and the solvent eliminated in vacuo without heating, to yield a yellow residue ... The search for selective histamine agonists and antag- onists remains one of the most active fields in medicinal chemistry. ... 3212 J. Org. ...