Tetrahedron

Tributylstibine mediated synthesis of 1, 1, 2-tri-substituted cyclopropanes

C Chen, L Yi, H Yao-Zeng

Index: Chen, Chen; Liao, Yi; Huang, Yao-Zeng Tetrahedron, 1989 , vol. 45, # 10 p. 3011 - 3020

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Citation Number: 24

Abstract

A novel method for the synthesis of 1, 1, 2-tri-substituted cyclopropanes is reported which involves the reaction of electron-deficient olefins with dibromomalonic ester, dibromocyanoacetic or dibromobenzene-acetic ester promoted by tri-n-butylstibine. The reaction was carried out under mild conditions to give the cyclopropane derivatives in moderate to good yields. Other R3M (M= As, Sb, Bi) reagents as promoter for this reaction ...