Synthesis and SAR of tetracyclic pyrroloquinolones as phosphodiesterase 5 inhibitors

W Jiang, VC Alford, Y Qiu, S Bhattacharjee…

Index: Bioorganic and Medicinal Chemistry, , vol. 12, # 6 p. 1505 - 1515

Full Text: HTML

Citation Number: 25

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. Volume 12, Issue 6, 15 March 2004, Pages 1505–1515. ... Pharmaceutical Research & Development, LLC, 1000 Route 202 South; PO Box 300, Raritan, NJ 08869, USA. ...

Related Articles:

Synthesis of tadalafil (Cialis) from l-tryptophan

[Xiao, Sen; Shi, Xiao-Xin; Xing, Jing; Yan, Jing-Jing; Liu, Shi-Ling; Lu, Wei-Dong Tetrahedron Asymmetry, 2009 , vol. 20, # 18 p. 2090 - 2096]

Two concise syntheses of cialis via the N-acyliminium Pictet-Spengler reaction

[Revell, Jefferson D.; Srinivasan, Natarajan; Ganesan Synlett, 2004 , # 8 p. 1428 - 1430]

Alternative synthesis of tadalafil: PDE5 inhibitor

[Anumula, Raghupathi Reddy; Madivada, Lokeswara Rao; Gilla, Goverdhan; Raju, V. V. N. K. Prasad; Kagga, Mukkanti; Reddy, Padi Pratap; Bhattacharya, Apurba; Bandichhor, Rakeshwar Synthetic Communications, 2008 , vol. 38, # 23 p. 4265 - 4271]

The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2, 3, 6, 7, 12, 12a-hexahydropyrazino [1', 2': 1, 6] pyrido [3, 4-b] indole-1, 4-dione analogues

[Journal of Medicinal Chemistry, , vol. 46, # 21 p. 4533 - 4542]

Microwave-assisted synthesis of tetracyclic 2, 5-diketopiperazines on a soluble polymer support: a structural analogue of Tadalafil

[Australian Journal of Chemistry, , vol. 62, # 1 p. 42 - 50]

More Articles...