1, 4??Thienodiazepine??2, 5??diones via MCR (I): Synthesis, Virtual Space and p53??Mdm2 Activity

Y Huang, S Wolf, M Bista, L Meireles…

Index: Chemical Biology and Drug Design, , vol. 76, # 2 p. 116 - 129

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Citation Number: 39

Abstract

... 3 Department of Computational Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA. ... As the father of modern MCR chemistry, Ivar Ugi pointed out in 1971 'if, for example ... RandReactor was written to provide smaller random sublibraries of such very large chemical spaces. ...