Chemical biology & drug design

1, 4??Thienodiazepine??2, 5??diones via MCR (II): Scaffold Hopping by Gewald and Ugi??Deprotection??Cyclization Strategy

Y Huang, A Dömling

Index: Chemical Biology and Drug Design, , vol. 76, # 2 p. 130 - 141

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Citation Number: 18

Abstract

... However, chemical space and the structural biology of 1,4-thienodiazepines are still largely ... Multicomponent reaction (MCR) chemistry is particularly useful for the fast and efficient discovery of ... The conformation analysis and chemical space of this novel scaffold was studied. ...

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