Fluorinated heterocycles: targets in the search for bioactive compounds and tools for their preparation

E Differding, W Frick, RW Lang, P Martin…

Index: Differding, E.; Frick, W.; Lang, R. W.; Martin, P.; Schmit, C.; et al. Bulletin des Societes Chimiques Belges, 1990 , vol. 99, # 9 p. 647 - 671

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Citation Number: 54

Abstract

ABSTRACT Two strategies for the preparation and use of fluorinated heterocycles are discussed:* the building block approach being used mainly for the preparation of target heterocycles with fluorinated substituents, and* the direct fluorination approach in which fluorinated heterocycles are used as tools for the preparation of bioactive compounds. Strategies presented in the building block approach include electrophilic reactions of ...

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