Reaction of β??Lapachone with 1, 2??Diamines: Facile Synthesis of Novel Tetracyclic Pyrazines

P Singh, A Dandia, K Natani, V Sharma…

Index: Singh, Pahup; Dandia, Anshu; Natani, Kavita; Sharma, Venu; Ratnani, Raju; Bingham; Hursthouse; Light; Drake Synthetic Communications, 2007 , vol. 37, # 1 p. 113 - 118

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Citation Number: 4

Abstract

Abstract The reactions of β??lapachone (1) with 1, 2??diaminoethane (2) and 1, 2?? diaminopropane (4) gave the tetracyclic pyrazine derivatives (3) and mixtures of (5) and (6), respectively, while reaction with o??phenylene diamine (7) gave the quinoxaline derivative (8). The structure of pyrazine derivative (3) is confirmed by single??crystal X??ray diffraction study.