Novel task-specific ionic liquids as solvents for michael addition of methylene active compounds to chalcones without any catalyst

…, XZ Chen, CL Wu, RH Zheng, HD Liang…

Index: Ying, An-Guo; Chen, Xin-Zhi; Wu, Cheng-Lin; Zheng, Ren-Hua; Liang, Hua-Ding; Ge, Chang-Hua Synthetic Communications, 2012 , vol. 42, # 23 p. 3455 - 3462

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Citation Number: 9

Abstract

Michael addition is one of the most simple, efficient, and atom-economical methodologies for carbon–carbon bond formation, which is central to organic synthesis. It is usually performed in organic solvents in the presence of strong bases that often lead to side reactions. Thus, many more efficient and milder catalysts, including 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), [ 1 1. Ye , WP ; Xu , JY ; Tan , CT ; Tan , CH 1,5,7-Triazabicyclo[4.4.0]dec-5-ene ...