Synlett

Beneficial Effect of Mukaiyama Reagent on Macrobislactamization Reactions

L Vandromme, D Monchaud, MP Teulade-Fichou

Index: Vandromme, Lucie; Monchaud, David; Teulade-Fichou, Marie-Paule Synlett, 2006 , # 20 p. 3423 - 3426

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Citation Number: 4

Abstract

Abstract An expeditious two-step procedure was developed to accede to new tetraamide macrocycles. The key step of this diversity-oriented procedure is a highly efficient Mukaiyama salt promoted macrobislactamization. Preliminary mechanistic investigations are also reported.

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