The Journal of Organic Chemistry

New Syntheses of Some Functionalized and Acetylenic. beta.-Keto Phosphonates

I Delamarche, P Mosset

Index: Delamarche, Isabelle; Mosset, Paul Journal of Organic Chemistry, 1994 , vol. 59, # 18 p. 5453 - 5457

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Citation Number: 35

Abstract

P-Keto phosphonates are valuable intermediates for organic synthesis, especially for the preparation of a, P-unsaturated carbonyl compounds by the Horner-Wadsworth-Emmons (HWE) reaction.'Various routes to/?-keto phosphonates are known and could be mainly classified in four types. First, the Arbuzov reaction of trialkyl phosphites with a-halo ketones leads, however, to mixtures of keto phosphonates and enol phosphates (resulting from a ...