Calcium??Catalyzed Friedel–Crafts Alkylation at Room Temperature

M Niggemann, MJ Meel

Index: Niggemann, Meike; Meel, Matthias J. Angewandte Chemie - International Edition, 2010 , vol. 49, # 21 p. 3684 - 3687

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Citation Number: 105

Abstract

Friedel–Crafts reactions are among the oldest and most efficient CÀC bond-forming processes for the functionalization of aromatic compounds.[1] A vivid interest in the synthesis of polycyclic aromatics, core structures of innumerable, biologically active natural products having continuing industrial and academic impact, has recently revived the research field of Friedel–Crafts reactions.[2] Most of the original Friedel–Crafts procedures have now been ...