Divergent synthesis of 1, 3-and 1, 4-diketones from β-methoxy-γ-phenylthio ketones accessible through novel phenylthio migration reaction

T Sato, M Inoue, S Kobara, J Otera, H Nozaki

Index: Sato, Tsuneo; Inoue, Masami; Kobara, Satoru; Otera, Junzo; Nozaki, Hitosi Tetrahedron Letters, 1989 ,  vol. 30,  # 1  p. 91 - 94

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Citation Number: 15

Abstract

Abstract Both 1, 3-and 1, 4-diketones are obtained from common precursors, β-methoxy-γ- phenylthio ketones. These compounds are derived through the novel phenylthio migration reaction of the aldehyde adducts with methoxy (phenylthio)-methane upon exposure to enol silyl ethers. The compounds thus obtained are converted into 1, 3-and 1, 4-diketones.