Quantitative structure-activity relationships of antibacterial agents, 7-heterocyclic amine substituted 1-cyclopropyl-6, 8-difluoro-4-oxoquinoline-3-carboxylic acids.

岡田哲夫， 江角清志， 山川眞透， 佐藤久夫…

Index: Chemical and Pharmaceutical Bulletin, , vol. 41, # 1 p. 126 - 131

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Citation Number: 33

Abstract

... activity; logP; parabolic relationship The last three decades in medicinal chemistry have been ... R6 R7 X R1 verifying relationships between antibacterial activity and chemical structure, markedly ... length and width and the level of unsaturation of © 1993 Pharmaceutical Society of ...