Simple and efficient CuI/PEG-400 system for amination of aryl halides with aqueous ammonia
J Chen, T Yuan, W Hao, M Cai
Index: Chen, Junmin; Yuan, Tangjun; Hao, Wenyan; Cai, Mingzhong Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3710 - 3713
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Citation Number: 36
Abstract
Abstract The cross-coupling reaction between aryl halides with aqueous ammonia was efficiently catalyzed in CuI/PEG-400 System with high yield. A range of electron-withdrawing or electron-donating aryl iodides and bromides were found to be applicable to the environmentally benign system. The process allows assembly of primary arylamines in great diversity which bear a wide range of functional groups including cyano, nitro, acetyl, ether, ...
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