Applications of 1??alkoxycarbonyl??and 1??acyl??v??triazolo [4, 5??b] pyridines as acylating reagents

…, GP Zecchini, F Agrosì, MP Paradisi

Index: Torrini, Ines; Zecchini, Giampiero Pagani; Agrosi, Francesco; Paradisi, Mario Paglialunga Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 1459 - 1463

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Citation Number: 12

Abstract

Abstract Selective N-protection of hydroxyamino esters has been readily achieved using 1- alkoxycarbonyl-or 1-acyl-v-triazolo [4, 5-b] pyridines. The amide-type triazolides reacted with alcohols in the presence of DBU at room temperature to afford in high yields the corresponding esters. The different reactivity of 1-and 3-alkoxycarbonyl derivatives of the title bicyclic system toward primary amines has been further investigated.

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