In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion.

N V S Cruz, J P Pessan, M M Manarelli, M D B Souza, A C B Delbem

Index: Arch. Oral Biol. 60 , 1231-6, (2015)

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Abstract

To evaluate the effect of a low-fluoride dentifrice (LFD) containing sodium trimetaphosphate (TMP) on enamel erosion in vitro.Bovine enamel blocks (n=144) were selected by surface hardness (SH) and subjected to erosive challenges, in two sets of experiments for 2 and 5 days. Blocks were randomly assigned to groups treated with slurries (5mL/block, for 15s) of following dentifrices: Placebo (no fluoride or TMP); LFD (250ppm F); LFD plus 0.25, 0.5, or 1.0% TMP; and a commercial positive control (1,425ppm F). The erosive challenge was produced by immersion in a soft drink (pH 2.8) for 5min, four times/day, interspersed by immersion in artificial saliva for 1h. SH and surface wear were analyzed as response variables. Data were submitted to 2-way ANOVA, followed by Student-Newman-Keuls test (p<0.05).All groups treated with LFDs containing TMP had significantly lower enamel wear when compared with the other groups tested (p<0.001). Also, the LFDs containing TPM at lower concentrations promoted SH similar to the commercial positive control, both being significantly higher than the LFD without TMP and Placebo (p<0.001).The supplementation of LFDs with TMP is able to significantly increase the anti-erosive potential of these formulations in vitro.Copyright © 2015 Elsevier Ltd. All rights reserved.