Synthesis and biological evaluations of quinoline-based HMG-CoA reductase inhibitors

M Suzuki, H Iwasaki, Y Fujikawa, M Kitahara…

Index: Bioorganic and Medicinal Chemistry, , vol. 9, # 10 p. 2727 - 2743

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Citation Number: 94

Abstract

... Bioorganic & Medicinal Chemistry. ... discovery of the naturally occurring fungal metabolites compactin 2a,b and lovastatin, 2c,d and the microbially transformed pravastatin, 2e a HMG-CoA reductase inhibitor has been the most attractive target for medicinal researchers. ... Chemistry. ...