Journal of Agricultural and Food Chemistry 2014-06-11

Alternative eluent composition for LC-MS analysis of perfluoroalkyl acids in raw fish samples.

Tõiv Haljasorg, Jaan Saame, Karin Kipper, Anu Teearu, Koit Herodes, Mari Reinik, Ivo Leito

Index: J. Agric. Food Chem. 62(23) , 5259-68, (2014)

Full Text: HTML

Abstract

A wide range of anthropogenic pollutants that possess serious environmental and health risks are known. One type of these harmful substances that have become a focus of interest during the past decade are perfluoroalkyl acids (PFAAs), which are extensively used in industry for different purposes. Due to the harmful effects that these compounds might cause in living organisms, EFSA and EU CONTAM panel have issued a monitoring program for PFAAs in foodstuffs. This has given rise to intense research dedicated to the analysis of PFAAs over the past few years. This work focuses on chromatographic analysis of three PFAAs in fish. The analytes, perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorooctanesulfonic acid (PFOS), are commonly associated with the production of fluoropolymers. Fluorinated alcohols are used as eluent components, and their possible advantages as eluent modifiers in LC-MS analysis of PFAAs, alternative retention mechanism and enhanced ionization efficiency, are examined. The analyzed fish samples originating from Estonian fresh and marine waters had low contents of PFAAs.

Related Compounds

  • Formic Acid
  • Ammonium acetate
  • Acetonitrile
  • Methanol
  • Aqueous ammonia
  • magnesium sulfate
  • Perfluorooctanoic...
  • Hexafluoroisopropa...

Related Articles:

Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson's disease.

2015-01-15

[J. Ethnopharmacol. 159 , 93-101, (2014)]

Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.

2014-11-01

[J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014)]

Methionine oxidation accelerates the aggregation and enhances the neurotoxicity of the D178N variant of the human prion protein.

2014-12-01

[Biochim. Biophys. Acta 1842(12 Pt A) , 2345-56, (2014)]

Quantification of furanic derivatives in fortified wines by a highly sensitive and ultrafast analytical strategy based on digitally controlled microextraction by packed sorbent combined with ultrahigh pressure liquid chromatography.

2015-02-13

[J. Chromatogr. A. 1381 , 54-63, (2015)]

Silencing urease: a key evolutionary step that facilitated the adaptation of Yersinia pestis to the flea-borne transmission route.

2014-12-30

[Proc. Natl. Acad. Sci. U. S. A. 111(52) , 18709-14, (2014)]

More Articles...