Chemical Communications 2011-04-21

DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker.

Katarzyna Gorska, Alex Manicardi, Sofia Barluenga, Nicolas Winssinger

Index: Chem. Commun. (Camb.) 47(15) , 4364-66, (2011)

Full Text: HTML

Abstract

Nucleic acid templated reactions have attracted significant attention for nucleic acid sensing. Herein we report a general design which extends the potential of nucleic acid templated reactions to unleash the function of a broad diversity of small molecules such as a transcription factor agonist, a cytotoxic or a fluorophore.© The Royal Society of Chemistry 2011


Related Compounds

  • 4-Aminobenzyl alco...

Related Articles:

Design, synthesis, and biological evaluation of a dual tumor-specific motive containing integrin-targeted plasmin-cleavable doxorubicin prodrug.

2002-09-01

[Mol. Cancer Ther. 1(11) , 901-11, (2002)]

Starch-based biodegradable hydrogels with potential biomedical applications as drug delivery systems.

2002-05-01

[Biomaterials 23(9) , 1955-66, (2002)]

A novel 4-aminobenzyl ester-based carboxy-protecting group for synthesis of atypical peptides by Fmoc-But solid-phase chemistry. Chan WC, et al.

[J. Chem. Soc. Chem. Commun. 21 , 2209-10, (1995)]

More Articles...