Synthesis of thiophene-2-carboxamidines containing 2-amino-thiazoles and their biological evaluation as urokinase inhibitors

KJ Wilson, CR Illig, N Subasinghe, JB Hoffman…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 7 p. 915 - 918

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Citation Number: 108

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... The replacement of the thiomethyl by methyl in the thiophene derivatives 8, 13, 14, and 44 was also performed for SAR comparison using chemistry recently communicated from our laboratories. 19. ...

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