Journal of Chromatography A 2012-01-01

Binding mechanisms for histamine and agmatine ligands in plasmid deoxyribonucleic acid purifications

Ângela Sousa, Patrícia Pereira, Fani Sousa, João A. Queiroz

Index: J. Chromatogr. A. 1366 , 110-9, (2014)

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Abstract

• The versatility of histamine and agmatine ligands in function of binding and elution conditions. • Histamine and agmatine-pDNA multiple interactions depend of salts, ionic strength and pH. • Both ligands showed a biorecognition to the sc pDNA isoform. • The binding and elution conditions affect the pDNA structural stability.

Related Compounds

  • sodium chloride
  • Trometamol
  • ammonium sulphate
  • Citric Acid
  • SODIUM CHLOR...
  • Ampicillin Trihyd...
  • Histamine dihydroc...
  • Histamine
  • Ampicillin
  • UNII:TF4710DNP...

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