Folate antagonists. 17. Synthesis and biological properties of a 2, 4??diamino??6??thioquinazoline analog of aminopterin

LM Werbel, L Newton…

Index: Journal of Heterocyclic Chemistry, , vol. 17, # 3 p. 497 - 500

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Citation Number: 6

Abstract

... ».o2c-f\ss/Aco^ 2 HCl -> Ho2c-r ^Vsh+ciY/ Yno2 •oo Chemistry. The route to 2 is shown in Schemes I and II. ... Heterocyclic Chem., 17, 501 (1980). ... 1562 to the Army Research Program in malaria. (3) EF Elslager, P. Jacob, J. Johnson, LM Werbel, DF Worth and L. Rane, J. Med. ...

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